|
KMID : 0882420070730001085
|
|
Korean Journal of Medicine
2007 Volume.73 No. 0 p.1085 ~ p.1089
|
|
|
A case of Reiter’s syndrome that was treated with etanercept
|
|
Yoo Hyun-Seung
Jo Ji-Hoon
Lee Su-Ee
Lee Jae-Hoon
Lee Chae-Wook
Lee Sung-Won
Chung Won-Tae
|
|
|
Abstract
|
|
|
|
Reiter’s syndrome is the combination of three symptoms: an inflammatory arthritis of large joints, inflammation of the eyes (conjunctivitis and uveitis) and urethritis. NSAIDs, steroids, antibiotics and immunosuppressive agents are used for the treatment of the Reiter’s syndrome. Tumor necrosis factor-α (TNF-α), which has been linked to the immune system and inflammation, plays an important role in the pathogenesis of rheumatoid arthritis (RA) and ankylosing spondylitis (AS). So, TNF- inhibitor is established as an important and effective therapy for both RA and AS to decrease joint pain and synovial inflammation. An elevated level of TNF-α has been identified in Reiter’s syndrome. This finding has provided a rationale for use of TNF-α inhibitors in the treatment of Reiter’s syndrome. We investigated a case of Reiter’s syndrome in a 24-year-old male who has failed with receiving sulfasalazine, indomethacin and steroid. Yet after using a TNF-α inhibitor, the polyarthritis, urethritis and skin lesions improved. (Korean J Med 73:S1085-S1089, 2007)
|
|
|
KEYWORD
|
|
|
Reiter’s syndrome, TNF-α inhibitor
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|